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OEL & API categorization

National Requirements or Safebridge banding scheme must be implemented in order to guarantee the health and safety of the staff involved in pharmaceutical manufacturing processes. It is necessary to determine an upper limit for any API in the workplace air (Occupational exposure limit) and establish relations between its toxicological and pharmacological properties and prevention measures.

API categorization is the way to establish that links between OELs and safety measures (engineering control, standardized work processes and safety equipment)

Our team of toxicology experts certified by AETOX, EUROTOX and ERT can provide this categorization through a scientific based evaluation which consists on:

  • Bibliographic search to review all the relevant information related to the API.
  • OEL Determination following international and widely accepted guidelines.
  • Categorization for the specific work conditions of any laboratory according with the National requirements or Safebridge banding scheme.

The outcome is a high quality and tailored written report where you can find comments and recommendations in order to assure health and safety for a specific workplace.


Access to OEL API Reports

At Azierta, we are experts in exposure limits (OEL), categorization of APIs and health surveillance protocols.

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  • Moderate toxicity
  • High toxicity
  • Very high toxicity
  • Potent toxicity

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  • Acepromazine maleate

    CAS: 3598-37-6

  • Acetylcysteine

    CAS: 616-91-1

  • Acetylsalicylic acid

    CAS: 50-78-2

  • Ademetionine

    CAS: 29908-03-0

  • Alfacalcidol

    CAS: 41294-56-8

  • Amamatidine hydrochloride

    CAS: 665-66-7

  • Amlodipine besylate

    CAS: 111470-99-6

  • Amorolfine

    CAS: 78613-35-1

  • Anastrozol

    CAS: 120511-73-1

  • Apixaban

    CAS: 503612-47-3

  • Aripiprazole

    CAS: 129722-12-9

  • Ascorbic acid

    CAS: 50–81–7

  • Atenolol

    CAS: 29122-68-7

  • Atipamezole hydrochloride

    CAS: 104075-48-1

  • Atorvastatin calcium

    CAS: 134523-03-8

  • Azacitidine

    CAS: 320-67-2

  • Azelastine

    CAS: 79307-93-0

  • Azitromycin dihydrate

    CAS: 117772-70-0

  • Acepromazine maleate

    CAS: 3598-37-6

  • Acetylcysteine

    CAS: 616-91-1

  • Acetylsalicylic acid

    CAS: 50-78-2

  • Ademetionine

    CAS: 29908-03-0

  • Alfacalcidol

    CAS: 41294-56-8

  • Amamatidine hydrochloride

    CAS: 665-66-7

  • Amlodipine besylate

    CAS: 111470-99-6

  • Amorolfine

    CAS: 78613-35-1

  • Anastrozol

    CAS: 120511-73-1

  • Apixaban

    CAS: 503612-47-3

  • Aripiprazole

    CAS: 129722-12-9

  • Ascorbic acid

    CAS: 50–81–7

  • Atenolol

    CAS: 29122-68-7

  • Atipamezole hydrochloride

    CAS: 104075-48-1

  • Atorvastatin calcium

    CAS: 134523-03-8

  • Azacitidine

    CAS: 320-67-2

  • Azelastine

    CAS: 79307-93-0

  • Azitromycin dihydrate

    CAS: 117772-70-0

  • Baclofen

    CAS: 1134-47-0

  • Benazepril

    CAS: 86541-75-5

  • Benzocaine

    CAS: 94-09-7

  • Betahistidine dihydrochloride

    CAS: 5579-84-0

  • Bilastine

    CAS: 202189-78-4

  • Bismuth subcitrate

    CAS: 57644-54-9

  • Bisoprolol fumarate

    CAS: 104344-23-2

  • Bosutinib

    CAS: 380843-75-4

  • Budenoside

    CAS: 51333-22-3

  • Baclofen

    CAS: 1134-47-0

  • Benazepril

    CAS: 86541-75-5

  • Benzocaine

    CAS: 94-09-7

  • Betahistidine dihydrochloride

    CAS: 5579-84-0

  • Bilastine

    CAS: 202189-78-4

  • Bismuth subcitrate

    CAS: 57644-54-9

  • Bisoprolol fumarate

    CAS: 104344-23-2

  • Bosutinib

    CAS: 380843-75-4

  • Budenoside

    CAS: 51333-22-3

  • Cabozantinib maleate

    CAS: 849217-68-1

  • Caffeine

    CAS: 58-08-2

  • Calcifediol

    CAS: 19356-17-3

  • Calcipotriol

    CAS: 112965-21-6

  • Calcitriol

    CAS: 32222-06-3

  • Canagliflozin hemihydrate

    CAS: 928672-86-0

  • Candesartan Cilexetil

    CAS: 145040-37-5

  • Captopril

    CAS: 62571-86-2

  • Carprofen

    CAS: 53716-49-7

  • Cefixime trihydrate

    CAS: 125110-14-7

  • Celecoxib

    CAS: 169590-42-5

  • Cephalexin hydrate

    CAS: 23325-78-2

  • Cetirizine hydrochloride

    CAS: 83881-52-1

  • Chloroquine phosphate

    CAS: 50-63-5

  • Chlorpheniramine maleate

    CAS: 113-92-8

  • Ciprofibrate

    CAS: 52214-84-3

  • Ciprofloxacin

    CAS: 85721-33-1

  • Ciproterone acetate

    CAS: 427-51-0

  • Citalopram

    CAS: 59729-32-8

  • Claritromycin

    CAS: 81103-11-9

  • Clomiphene citrate

    CAS: 50-41-9

  • Clonidine hydrochloride

    CAS: 4205-91-8

  • Clopidogrel hydrogen sulfate

    CAS: 120202-66-6

  • Clozapine

    CAS: 5786-21-0

  • Codeine phosphate

    CAS: 52-28-8

  • Cyanocobalamin

    CAS: 68-19-9

  • Cabozantinib maleate

    CAS: 849217-68-1

  • Caffeine

    CAS: 58-08-2

  • Calcifediol

    CAS: 19356-17-3

  • Calcipotriol

    CAS: 112965-21-6

  • Calcitriol

    CAS: 32222-06-3

  • Canagliflozin hemihydrate

    CAS: 928672-86-0

  • Candesartan Cilexetil

    CAS: 145040-37-5

  • Captopril

    CAS: 62571-86-2

  • Carprofen

    CAS: 53716-49-7

  • Cefixime trihydrate

    CAS: 125110-14-7

  • Celecoxib

    CAS: 169590-42-5

  • Cephalexin hydrate

    CAS: 23325-78-2

  • Cetirizine hydrochloride

    CAS: 83881-52-1

  • Chloroquine phosphate

    CAS: 50-63-5

  • Chlorpheniramine maleate

    CAS: 113-92-8

  • Ciprofibrate

    CAS: 52214-84-3

  • Ciprofloxacin

    CAS: 85721-33-1

  • Ciproterone acetate

    CAS: 427-51-0

  • Citalopram

    CAS: 59729-32-8

  • Claritromycin

    CAS: 81103-11-9

  • Clomiphene citrate

    CAS: 50-41-9

  • Clonidine hydrochloride

    CAS: 4205-91-8

  • Clopidogrel hydrogen sulfate

    CAS: 120202-66-6

  • Clozapine

    CAS: 5786-21-0

  • Codeine phosphate

    CAS: 52-28-8

  • Cyanocobalamin

    CAS: 68-19-9

  • Dalbavancin

    CAS: 171500-79-1

  • Danazol

    CAS: 17230-88-5

  • Dantrolene sodium

    CAS: 14663-23-1

  • Dapaglifozin

    CAS: 461432-26-8

  • Desloratadine

    CAS: 100643-71-8

  • Desoxycorticosterone pivalate

    CAS: 808-48-0

  • Dexamethasone acetate

    CAS: 50-02-2

  • Dexketoprofen trometamol

    CAS: 156604-79-4

  • Dexmedetomidine hydrochloride

    CAS: 145108-58-3

  • Dibucaine (Cinchocaine)

    CAS: 61-12-1

  • Diclofenac sodium

    CAS: 15307-79-6

  • Dicycloverine hydrochloride

    CAS: 67-92-5

  • Diethanolamine fusidate

    CAS: 16391-75-6

  • Diltiazem hydrochloride

    CAS: 33286-22-5

  • Diosmin

    CAS: 520-27-4

  • Donepezil hydrochloride

    CAS: 120011-70-3

  • Doxercalciferol

    CAS: 54573-75-0

  • Drotaverine hydrochloride

    CAS: 985-12-6

  • Dalbavancin

    CAS: 171500-79-1

  • Danazol

    CAS: 17230-88-5

  • Dantrolene sodium

    CAS: 14663-23-1

  • Dapaglifozin

    CAS: 461432-26-8

  • Desloratadine

    CAS: 100643-71-8

  • Desoxycorticosterone pivalate

    CAS: 808-48-0

  • Dexamethasone acetate

    CAS: 50-02-2

  • Dexketoprofen trometamol

    CAS: 156604-79-4

  • Dexmedetomidine hydrochloride

    CAS: 145108-58-3

  • Dibucaine (Cinchocaine)

    CAS: 61-12-1

  • Diclofenac sodium

    CAS: 15307-79-6

  • Dicycloverine hydrochloride

    CAS: 67-92-5

  • Diethanolamine fusidate

    CAS: 16391-75-6

  • Diltiazem hydrochloride

    CAS: 33286-22-5

  • Diosmin

    CAS: 520-27-4

  • Donepezil hydrochloride

    CAS: 120011-70-3

  • Doxercalciferol

    CAS: 54573-75-0

  • Drotaverine hydrochloride

    CAS: 985-12-6

  • Ebastine

    CAS: 90729-43-4

  • EDTA disodium

    CAS: 6381-92-6

  • Eldecalcitol

    CAS: 104121-92-8

  • Embutramide

    CAS: 15687-14-6

  • Empagliflozin

    CAS: 864070-44-0

  • Enalapril maleate

    CAS: 76095-16-4

  • Enrofloxacin

    CAS: 106-60-6

  • Ergocalciferol

    CAS: 50-14-6

  • Eribulin

    CAS: 253128-41-5

  • Escitalopram oxalate

    CAS: 219861-08-2

  • Eslicarbazepine

    CAS: 236395-14-5

  • Ethinylestradiol

    CAS: 57-63-6

  • Ethynodiol diacetate

    CAS: 297-76-7

  • Etoricoxib

    CAS: 202409-33-4

  • Ezetimibe

    CAS: 163222-33-1

  • Ebastine

    CAS: 90729-43-4

  • EDTA disodium

    CAS: 6381-92-6

  • Eldecalcitol

    CAS: 104121-92-8

  • Embutramide

    CAS: 15687-14-6

  • Empagliflozin

    CAS: 864070-44-0

  • Enalapril maleate

    CAS: 76095-16-4

  • Enrofloxacin

    CAS: 106-60-6

  • Ergocalciferol

    CAS: 50-14-6

  • Eribulin

    CAS: 253128-41-5

  • Escitalopram oxalate

    CAS: 219861-08-2

  • Eslicarbazepine

    CAS: 236395-14-5

  • Ethinylestradiol

    CAS: 57-63-6

  • Ethynodiol diacetate

    CAS: 297-76-7

  • Etoricoxib

    CAS: 202409-33-4

  • Ezetimibe

    CAS: 163222-33-1

  • Famotidine

    CAS: 76824-35-6

  • Febantel

    CAS: 58306-30-2

  • Fentanyl citrate

    CAS: 990-73-8

  • Finasteride

    CAS: 98319-26-7

  • Fingolimod hydrochloride

    CAS: 162359-56-0

  • Florfenicol

    CAS: 73231-34-2

  • Flunixin meglumine

    CAS: 42461-84-7

  • Fluoxetine

    CAS: 54910-89-3

  • Flutamide

    CAS: 13311-84-7

  • Folic acid

    CAS: 59-30-3

  • Framycetin sulfate

    CAS: 4146-30-9

  • FSH (Follicle stimulating hormone )

    CAS: 9002-68-0

  • Furosemide

    CAS: 54-31-9

  • Famotidine

    CAS: 76824-35-6

  • Febantel

    CAS: 58306-30-2

  • Fentanyl citrate

    CAS: 990-73-8

  • Finasteride

    CAS: 98319-26-7

  • Fingolimod hydrochloride

    CAS: 162359-56-0

  • Florfenicol

    CAS: 73231-34-2

  • Flunixin meglumine

    CAS: 42461-84-7

  • Fluoxetine

    CAS: 54910-89-3

  • Flutamide

    CAS: 13311-84-7

  • Folic acid

    CAS: 59-30-3

  • Framycetin sulfate

    CAS: 4146-30-9

  • FSH (Follicle stimulating hormone )

    CAS: 9002-68-0

  • Furosemide

    CAS: 54-31-9

  • Gabapentin

    CAS: 60142-96-3

  • Gadobutrol

    CAS: 770691-21-9

  • Gatifloxacin

    CAS: 112811-59-3

  • Gentamicin sulphate

    CAS: 1405-41-0

  • Glibenclamide

    CAS: 10238-21-8

  • Glimepiride

    CAS: 93479-97-1

  • Gabapentin

    CAS: 60142-96-3

  • Gadobutrol

    CAS: 770691-21-9

  • Gatifloxacin

    CAS: 112811-59-3

  • Gentamicin sulphate

    CAS: 1405-41-0

  • Glibenclamide

    CAS: 10238-21-8

  • Glimepiride

    CAS: 93479-97-1

  • Hydrochlorothiazide

    CAS: 58-93-5

  • Hydrocortisone

    CAS: 50-23-7

  • Hydrochloroquine sulfate

    CAS: 747-36-4

  • Hydrochlorothiazide

    CAS: 58-93-5

  • Hydrocortisone

    CAS: 50-23-7

  • Hydrochloroquine sulfate

    CAS: 747-36-4

  • Ibersartan

    CAS: 138402-11-6

  • Ibuprofen

    CAS: 15687-27-1

  • Imatinib

    CAS: 152459-95-5

  • Isopropyl myristate

    CAS: 110-27-0

  • Isosorbide dinitrate

    CAS: 87-33-2

  • Ivabradine hydrochloride

    CAS: 148849-67-6

  • Ibersartan

    CAS: 138402-11-6

  • Ibuprofen

    CAS: 15687-27-1

  • Imatinib

    CAS: 152459-95-5

  • Isopropyl myristate

    CAS: 110-27-0

  • Isosorbide dinitrate

    CAS: 87-33-2

  • Ivabradine hydrochloride

    CAS: 148849-67-6

  • Ketamine hydrochloride

    CAS: 33795-24-3

  • Ketoconazole

    CAS: 65277-42-1

  • Ketotifen fumarate

    CAS: 34580-13-7

  • Ketamine hydrochloride

    CAS: 33795-24-3

  • Ketoconazole

    CAS: 65277-42-1

  • Ketotifen fumarate

    CAS: 34580-13-7

  • Lacosamide

    CAS: 175481-36-4

  • Lenvatinib

    CAS: 417716-92-8

  • Levamisole hydrochloride

    CAS: 16595-80-5

  • Levetiracetam

    CAS: 102767-28-2

  • Levocetirizine dihydrochloride

    CAS: 130018-87-0

  • Levodopa

    CAS: 59-92-7

  • Levofloxacin

    CAS: 100986-85-4

  • Lidocaine

    CAS: 137-58-6

  • Linagliptin

    CAS: 668270-12-0

  • Lincomycine hydrochloride

    CAS: 859-18-7

  • Lisdexamfetamine dimesylate

    CAS: 608137-33-3

  • Loperamide hydrochloride

    CAS: 34552-83-5

  • Losartan potassium

    CAS: 124750-99-8

  • Lysine clonixinate

    CAS: 55837-30-4

  • Lacosamide

    CAS: 175481-36-4

  • Lenvatinib

    CAS: 417716-92-8

  • Levamisole hydrochloride

    CAS: 16595-80-5

  • Levetiracetam

    CAS: 102767-28-2

  • Levocetirizine dihydrochloride

    CAS: 130018-87-0

  • Levodopa

    CAS: 59-92-7

  • Levofloxacin

    CAS: 100986-85-4

  • Lidocaine

    CAS: 137-58-6

  • Linagliptin

    CAS: 668270-12-0

  • Lincomycine hydrochloride

    CAS: 859-18-7

  • Lisdexamfetamine dimesylate

    CAS: 608137-33-3

  • Loperamide hydrochloride

    CAS: 34552-83-5

  • Losartan potassium

    CAS: 124750-99-8

  • Lysine clonixinate

    CAS: 55837-30-4

  • Maropitant citrate

    CAS: 359875-09-5

  • Maxacalcitol

    CAS: 103909-75-7

  • Medroxyprogesterone acetate

    CAS: 71-58-9

  • Meloxicam

    CAS: 71125-38-7

  • Memantine hydrochloride

    CAS: 41100-52-1

  • Metandrostenolone

    CAS: 72-63-9

  • Metformin

    CAS: 657-24-9

  • Methadone hydrochloride

    CAS: 1095-90-5

  • Methimazole

    CAS: 60-56-0

  • Methylprednisolone

    CAS: 83-43-2

  • Metoclopramide hydrochloride

    CAS: 7232-21-5

  • Metronidazole

    CAS: 443-48-1

  • Midazolam hydrochloride

    CAS: 59467-96-8

  • Mirtazapine

    CAS: 85650-52-8

  • Mometasone furoate

    CAS: 83919-23-7

  • Montelukast sodium

    CAS: 151767-02-1

  • Moroxydine hydrochloride

    CAS: 3160-91-6

  • Mycophenolate

    CAS: 24280-93-1

  • Myristyl-Gamma-Picolinium chloride

    CAS: 2748-88-1

  • Maropitant citrate

    CAS: 359875-09-5

  • Maxacalcitol

    CAS: 103909-75-7

  • Medroxyprogesterone acetate

    CAS: 71-58-9

  • Meloxicam

    CAS: 71125-38-7

  • Memantine hydrochloride

    CAS: 41100-52-1

  • Metandrostenolone

    CAS: 72-63-9

  • Metformin

    CAS: 657-24-9

  • Methadone hydrochloride

    CAS: 1095-90-5

  • Methimazole

    CAS: 60-56-0

  • Methylprednisolone

    CAS: 83-43-2

  • Metoclopramide hydrochloride

    CAS: 7232-21-5

  • Metronidazole

    CAS: 443-48-1

  • Midazolam hydrochloride

    CAS: 59467-96-8

  • Mirtazapine

    CAS: 85650-52-8

  • Mometasone furoate

    CAS: 83919-23-7

  • Montelukast sodium

    CAS: 151767-02-1

  • Moroxydine hydrochloride

    CAS: 3160-91-6

  • Mycophenolate

    CAS: 24280-93-1

  • Myristyl-Gamma-Picolinium chloride

    CAS: 2748-88-1

  • Naftazone

    CAS: 15687-37-3

  • Neohesperidin dihydrochalcone

    CAS: 20702-77-6

  • Neomycin sulfate

    CAS: 1405-10-3

  • Nifedipine

    CAS: 21829-25-4

  • Nitrendipine

    CAS: 39562-70-4

  • Nitroglicerin

    CAS: 55-63-0

  • Nystatin

    CAS: 1400-61-9

  • Naftazone

    CAS: 15687-37-3

  • Neohesperidin dihydrochalcone

    CAS: 20702-77-6

  • Neomycin sulfate

    CAS: 1405-10-3

  • Nifedipine

    CAS: 21829-25-4

  • Nitrendipine

    CAS: 39562-70-4

  • Nitroglicerin

    CAS: 55-63-0

  • Nystatin

    CAS: 1400-61-9

  • Ofloxacin

    CAS: 82419-36-1

  • Olanzapine

    CAS: 132539-06-1

  • Olaparib

    CAS: 763113-22-0

  • Olmesartan medoxomil

    CAS: 144689-63-4

  • Omeprazole

    CAS: 73590-58-6

  • Orphenadrine citrate

    CAS: 4682-36-4

  • Osimertinib mesylate

    CAS: 1421373-66-1

  • Oxytetracycline

    CAS: 79-57-2

  • Ofloxacin

    CAS: 82419-36-1

  • Olanzapine

    CAS: 132539-06-1

  • Olaparib

    CAS: 763113-22-0

  • Olmesartan medoxomil

    CAS: 144689-63-4

  • Omeprazole

    CAS: 73590-58-6

  • Orphenadrine citrate

    CAS: 4682-36-4

  • Osimertinib mesylate

    CAS: 1421373-66-1

  • Oxytetracycline

    CAS: 79-57-2

  • Pantoprazole sodium

    CAS: 138786-67-1

  • Paracalcitol

    CAS: 131918-61-1

  • Paracetamol

    CAS: 103-90-2

  • Paromomycine (aminosidine) sulfate

    CAS: 1263-89-4

  • Penciclovir

    CAS: 39809-25-1

  • Pentosan polysulphate sodium

    CAS: 140207-93-8

  • Perlagonium siloides

    CAS: -

  • Phenazopyridine

    CAS: 94-78-0

  • Phenobarbital

    CAS: 50-06-6

  • Phenylephrine

    CAS: 59-42-7

  • Phenylpropanolamine hydrochloride

    CAS: 154-41-6

  • Pidolate calcium

    CAS: 31377-05-6

  • Pimobendan

    CAS: 74150-27-9

  • Piperazine cirate

    CAS: 144-29-6

  • Piroxicam

    CAS: 36322-90-4

  • Pitavastatin calcium

    CAS: 147511-69-1

  • Pomalidomide

    CAS: 19171-19-8

  • Potassium bromide

    CAS: 7758-02-3

  • Pramipexole dihydrochloride monohydrate

    CAS: 191217-81-9

  • Pravastatin sodium

    CAS: 81131-70-6

  • Praziquantel

    CAS: 55268-74-1

  • Prednisolone

    CAS: 50-24-8

  • Pregabalin

    CAS: 148553-50-8

  • Procaine hydrochloride

    CAS: 51-05-8

  • Propinox hydrochloride

    CAS: 2765-97-1

  • Propyphenazone

    CAS: 479-92-5

  • Pyrantel pamoate

    CAS: 22204-24-6

  • Pyridostigmine bromide

    CAS: 101-26-8

  • Pantoprazole sodium

    CAS: 138786-67-1

  • Paracalcitol

    CAS: 131918-61-1

  • Paracetamol

    CAS: 103-90-2

  • Paromomycine (aminosidine) sulfate

    CAS: 1263-89-4

  • Penciclovir

    CAS: 39809-25-1

  • Pentosan polysulphate sodium

    CAS: 140207-93-8

  • Perlagonium siloides

    CAS: -

  • Phenazopyridine

    CAS: 94-78-0

  • Phenobarbital

    CAS: 50-06-6

  • Phenylephrine

    CAS: 59-42-7

  • Phenylpropanolamine hydrochloride

    CAS: 154-41-6

  • Pidolate calcium

    CAS: 31377-05-6

  • Pimobendan

    CAS: 74150-27-9

  • Piperazine cirate

    CAS: 144-29-6

  • Piroxicam

    CAS: 36322-90-4

  • Pitavastatin calcium

    CAS: 147511-69-1

  • Pomalidomide

    CAS: 19171-19-8

  • Potassium bromide

    CAS: 7758-02-3

  • Pramipexole dihydrochloride monohydrate

    CAS: 191217-81-9

  • Pravastatin sodium

    CAS: 81131-70-6

  • Praziquantel

    CAS: 55268-74-1

  • Prednisolone

    CAS: 50-24-8

  • Pregabalin

    CAS: 148553-50-8

  • Procaine hydrochloride

    CAS: 51-05-8

  • Propinox hydrochloride

    CAS: 2765-97-1

  • Propyphenazone

    CAS: 479-92-5

  • Pyrantel pamoate

    CAS: 22204-24-6

  • Pyridostigmine bromide

    CAS: 101-26-8

  • Quetiapine fumarate

    CAS: 111974-72-2

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